Using bioprocess containers for cell analysis

Cell analysis has aided research and drug development within the life science and pharmaceutical sectors for many years. Throughout our latest article, our specialists delve into the exciting world of cell analysis, exploring how it’s used and the developments it can lead to. We’ll also explore how bioprocess containers and bioprocess bags are utilised during this process, and why ALLpaQ systems – with the largest ranges in sizes and customisations available – are among the most popular on the market!

What is cell analysis?

Cell or cellular analysis is a broad term encompassing the methods and technologies used to study cells and their functions. Within this are multi-cell and single-cell analysis, the former centred around the study of a population of cells and the latter around individual cell behaviour within the same population.

Multi-cell or bulk investigations provide a general overview of the behaviour of a group of cells, but fail to offer detailed insights into the characteristics of individual cells within that population. 

Single-cell analysis, on the other hand, enables a richer understanding of cellular heterogeneity – this is where individual cells may behave differently from others, even if they’re in the same group.

Cell analysis, particularly of heterogeneity, is crucial in the research and development of biopharmaceutical products and life-saving cancer treatments. It also ensures high-quality product yields.

What are bioprocess bags used for in cell analysis?

Bioprocessing bags are flexible, single-use bags that are used to hold the media and research fluids used during cell analysis. These fluid media are required during bioprocessing and, in particular, cell analysis:

• Culture media – fluid formulas that provide the perfect conditions and nutrients cells need to grow and develop.
• Buffers – fluids that are used to stabilise pH levels.
• Sheath fluids – buffers that help single-cells to align ahead of analysis.
• Fixatives – to preserve cells and prevent bacterial growth before cellular analysis.

What are bioprocess containers used for in cell analysis?

Bioprocess containers, like the ones we manufacture, are outer-packaging units used to protect and house the bioprocessing bags mentioned above, so you could say they’re pretty important!

From shipping and warehouse storage to cleanroom applications, a robust and resilient poly bioprocess container will keep your fluids safely within, preventing leakage, biological hazards and cross-contamination between liquids during cell analysis.

A clean and sterile environment is essential in cleanrooms to prevent contamination during cellular analysis and drug production, and bioprocess containers can help you achieve this. Additionally, ALLpaQ offer Anti-Slosh devices designed by our tech team, and foam for lining the container under the single-use bag to further support and protect bioprocess bags.

Why choose ALLpaQ bioprocess containers for cell analysis?

If you want to improve your liquid handling applications to ensure sterility and process efficiency during cell analysis, you need a bioprocess container from ALLpaQ.

We’re experts in fluid-management systems, with our specialist containers being in demand by scientists across the globe. So, how have our totes made us market leaders in the field?

5 reasons to choose our bioprocess containers   

Reliable high-quality systems

Our experienced team manufactures liquid-handling containers in-house that you can depend on. From design to fabrication, we don’t settle for less than perfect when it comes to the totes we supply – in fact, we’re thrilled to announce that we have achieved ISO 9001 and 14001 certifications again, alongside EcoVadis Gold, reflecting our commitment to quality, efficiency, and environmental responsibility.

Your container won’t leave our manufacturing hub until rigorous quality checks have been performed, so you can relax knowing you’ll only receive a top-grade product. 

Compatibility

All our bioprocess containers are compatible with most media bag types, catering to your chosen cell analysis application, whatever it may be! We can even customise applications around bag dimensions.

Storage

Collapsible, stackable, and forklift-friendly thanks to a handy palletted base, ALLpaQ bioprocess containers boast an innovative design that makes storage and logistics as easy as pie. Not only this, but your tote can be folded away when not required, helping you to save huge amounts of floor space around your facility. 

Hygienic 

Our designs feature smooth walls that are easily cleaned for enhanced hygiene benefits – each wall panel is also removable and jet-washable for enhanced sterilisation. This means you don’t need to worry about contamination in your cleanroom while conducting your bioprocess applications, alongside a reduced risk of tears and rips.

Customisability 

Not sure if your unique bag requirements can be met by our range of bioprocessing containers? We can design and manufacture a bespoke model using the options from our existing fleet to ensure you can complete your applications as you need to. 

From shape and size to bag port positioning, we can adapt our fluid-management solutions to fit you with our custom bioprocess containers.  

Contact the ALLpaQ team

If your current fluid-management systems are holding your operations back and hindering your processes, it might be time to switch to our state-of-the-art solutions. Our highly-experienced team can work with you to pair you with your ideal bioprocess containers, taking into account your applications, bag requirements, and facility space.

To speak with our specialists now or request a callback, you can call us on 01472 800 373 or enquire online today, and we’ll be in touch.

Author

Niamh Allen

As a dedicated and detail-oriented Marketing Assistant, Niamh brings a strong passion for creativity and analytics to the marketing team.

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